Research Report: Trial tests stem cell treatment for heart failure

The UCSD Medical Center is the first hospital in California to enroll patients in a multi-center clinical trial to examine the safety and feasibility of administering adult stem cells to treat congestive heart failure. The cells, derived from bone marrow, are injected by a catheter directly into the heart muscle.

This Phase 2 clinical trial will evaluate whether or not adult stems cells can be targeted to the heart muscle to repair and help improve cardiac function in patients with severe heart disease. The hope is to identify an effective, minimally invasive treatment for the growing numbers of patients in the U.S. who suffer from advanced heart failure and have no other treatment alternatives. Heart failure affects more than five million patients in the United States.

‘Data deluge’
A recent study by the International Data Corp. (IDC) said that in 2007, the amount of digital data began to exceed the amount of storage to retain it, and will continue to grow faster than storage capacity from here on. The IDC study predicts that by 2011, our “digital universe” – consisting of digitally based text, video, images, music, etc. – will be 10 times the size it was in 2006.

A blue-ribbon task force – co-chaired by Fran Berman, Ph.D., director of the San Diego Supercomputer Center at UCSD – commissioned to identify sustainable economic models to provide access to the ever-growing amount of digital information in the public interest, has issued an interim report that calls the current data-storage situation urgent.

Although not all data should be preserved, digital data within the public interest – historical documents, research data sets, YouTube videos of presidential addresses, etc. – should be retained to maintain an accurate and complete digital record of society.

Visualizing at TSRI
Researchers at The Scripps Research Institute (TSRI) have discovered how a cell’s outer membrane pinches a little pouch (“vesicle”) from itself to bring molecules outside the cell inside – without making holes that leak fluid from either side of the membrane.

The process is possible only because a single molecule (dynamin) forms a short “collar” of proteins around a bit of the membrane that has emerged from the “parent” membrane, and then squeezes it tight, cleanly separating the new “daughter” vesicle.

Reporting in the journal Cell, the scientists describe creating a system in which they can watch the process, in real time, under a light microscope.

Related posts:

  1. Scripps research advances stem cell work
  2. UCSD researcher receives $1.5 million award
  3. UCSD adds power storage to fuel cell project
  4. Research Roundup: Basic research gets financial boost from major grants
  5. Research Roundup: Vitamin D may help prevent skin infections

Short URL: http://www.delmartimes.net/?p=6133

Posted by marylajolla on Jan 8, 2009. Filed under Archives. You can follow any responses to this entry through the RSS 2.0. You can leave a response or trackback to this entry

Leave a Reply

Archives

Facebook

Bottom Buttons 1

Bottom Buttons 2

Bottom Buttons 3

Bottom Buttons 4

Bottom Buttons 5

Bottom Buttons 6

LA JOLLA NEWS

RSS LA JOLLA NEWS

RANCHO SANTA FE NEWS

RANCHO SANTA FE NEWS

RSS RANCHO SANTA FE NEWS

  • San Diego realtor pleads guilty to prostitution-related crimes
    San Diego realtor Michael E. Lustig pleaded guilty in federal court July 31 to prostitution-related crimes, admitting that he paid for sex with a 13-year-old girl on several occasions. Lustig, who was indicted by a federal grand jury in October of 2013, entered his plea before U.S. Magistrate Judge Mitchell D. Dembin. (At that time Lustig was reported to be […]
  • It’s no stretch for Rancho Santa Fe yoga instructor to ‘give back’
    As one of North County’s most prolific yoga instructors, Stacy McCarthy doesn’t just teach yoga, she lives the yoga lifestyle. Selfless service, or seva in Sanskrit, is an important concept of yoga — one that the Rancho Santa Fe resident practices daily. “When we give and we give from the heart, there’s nothing more gratifying than that,” McCarthy said. […]
  • Rancho Santa Fe resident’s Gen 7 wines earn top honors
    Rancho Santa Fe resident Tim Bacino’s Gen 7 Wines is on a hot streak, his varietals winning several awards this summer in California wine competitions. […]