Safer stem cell method achieved

A group of researchers at The Scripps Research Institute (TSRI) and other institutions have made a significant advance in stem cell research by converting adult cells all the way back to the most primitive embryoniclike cells without using the undesirable genes or viruses associated with previous methods. The new method doesn’t require the destruction of an embryo.

The work builds on a groundbreaking technique developed a few years ago in Japan to coax adult skin cells back to a stem cell state. This was done by inserting genes to stimulate the production of proteins that triggered the transformation. Unfortunately, a number of safety concerns arose. Among them, the presence of foreign DNA in the cells made transplantation impractical.

The basis of the new TSRI method involves creation of the desired proteins outside of the cell and then inserting them, achieving the same results in a safer manner.

Having a source of the most primitive stem cells available would be useful in many medical situations because these cells are “pluripotent” (pluri – many, potent – power), with the ability to become any of the body’s cell types. Harnessing this ability could ultimately lead to the repair of damaged tissues throughout the body.

The current study is published online in the journal Cell Stem Cell.

Ocean initiative launched
The ocean is the planet’s largest ecosystem. Thanks to a $400 million Ocean Observatories Initiative (OOI), funded by the National Science Foundation, an array of more than 50 diverse sensor types and other scientific instruments will collect data and communicate through permanently installed seafloor cables and satellite telemetry.

In addition to the scientific community, teachers, students, and the general public will be able to view and interact with this data on the OOI Web site. Partners in the OOI network include the California Institute for Telecommunications and Information Technology (Calit2) and the Scripps Institution of Oceanography, both at UCSD. Final design approval from the NSF is expected later this spring.

Alcohol and teen brain
“White matter” is the part of the brain made up of axons, the long nerve fibers that carry the electrical signals between neurons (nerve cells) critical for relaying information within the brain. Researchers have long known that the integrity of white matter is compromised in adult alcoholics, but how early in life can damage begin?

A study by UCSD School of Medicine researchers of binge drinking by teenagers showed lower coherence of white matter fibers in a variety of regions in the still-developing brain.

Heavy episodic or “binge” drinking is common among adolescents, with 55 percent of high-school seniors reporting having gotten drunk, and a quarter of them reporting having consumed five or more drinks in a row.

Results will be published online in July in the journal Alcoholism: Clinical & Experimental Research.

Related posts:

  1. SRI eliminating the controversy in stem cell research
  2. Scripps research advances stem cell work
  3. Research Report: Trial tests stem cell treatment for heart failure
  4. Editorial: Stem cell move the right decision
  5. Proposed stem cell research center in TP may collapse

Short URL: http://www.delmartimes.net/?p=6310

Posted by marylajolla on Apr 30, 2009. Filed under Archives. You can follow any responses to this entry through the RSS 2.0. You can leave a response or trackback to this entry

Leave a Reply

Archives

Facebook

Bottom Buttons 1

Bottom Buttons 2

Bottom Buttons 3

Bottom Buttons 4

Bottom Buttons 5

Bottom Buttons 6

LA JOLLA NEWS

RSS LA JOLLA NEWS

  • La Jolla Library welcomes new chief Shaun Briley
    For La Jolla Riford Library’s new head librarian, Shaun Briley, books have been a part of his life and career, in some form or another, every step of the way. […]
  • Tangerine trees, marmalade skies for Beatles-inspired Patrons of the Prado gala in Balboa Park, San Diego
    “Lucy in the Sky with Diamonds” was the theme of the Patrons of the Prado gala on July 12, 2014 in Balboa Park, San Diego. Beatles-inspired music came from Wayne Foster Entertainment. Sandy Redman and Jeanne Jones served as event chairs. 2014’s beneficiaries are the Reuben H. Fleet Science Center, San Diego Museum of Art and The Old Globe Theatre. […]
  • La Jolla’s Best Bets for events July 31- Aug. 7
    Museum of Photographic Arts (MOPA) offers a crash course in starting a photography collection 6 p.m. Thursday Aug. 7. at the Ligne Roset Showroom, 7726 Girard Ave. MOPA assistant curator Chantel Paul and director of jdc Fine Art Jennifer DeCarlo will share professional insights. […]

RANCHO SANTA FE NEWS

RANCHO SANTA FE NEWS

RSS RANCHO SANTA FE NEWS

  • Rancho Santa Fe resident’s Gen 7 wines earn top honors
    Rancho Santa Fe resident Tim Bacino’s Gen 7 Wines is on a hot streak, his varietals winning several awards this summer in California wine competitions. […]
  • Torrey Pines High School baseball alum Taylor Murphy excelling in pro ball
    It was during a breakout senior year at Torrey Pines High that Taylor Murphy first popped up on the radar of professional scouts. Shortly after graduation, Murphy was selected by the San Diego Padres in the 40th round of the June 2011 amateur draft. He declined, honoring a commitment to the University of the Pacific. Three years later, Murphy got another sho […]
  • Why Hire a Licensed Landscape Professional?
    By Steve Jacobs, Nature Designs The old saying – “if something seems to good to be true, it probable is” – is quite fitting when it comes to hiring a contractor for your home or yard construction project. While it is smart to shop around, get quotes, etc., don’t fall into the trap of trusting […]